The Multiple Sclerosis Functional Composite and Symbol Digit Modalities Test as outcome measures in pediatric multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis
Cognitive and motor performance measures are commonly employed in multiple sclerosis (MS) research, particularly when the purpose is to determine the efficacy of treatment. The increasing focus of new therapies on slowing progression or reversing neurological disability makes the utilization of sensitive, reproducible, and valid measures essential. Processing speed is a basic elemental cognitiv...
متن کاملThe Symbol Digit Modalities Test is an effective cognitive screen in pediatric onset multiple sclerosis (MS).
OBJECTIVE To evaluate the Symbol Digit Modalities Test (SDMT) as a tool for identifying pediatric-onset MS patients at risk for cognitive impairment. BACKGROUND The SDMT is a brief measure of cognitive processing speed that is often used in adult MS patients. Approximately one-third of pediatric-onset MS patients have cognitive impairment and there is a need for an effective screening instrum...
متن کاملEye and hand motor interactions with the Symbol Digit Modalities Test in early multiple sclerosis.
PURPOSE Eye and hand motor dysfunction may be present early in the disease course of relapsing-remitting multiple sclerosis (RRMS), and can affect the results on visual and written cognitive tests. We aimed to test for differences in saccadic initiation time (SI time) between RRMS patients and healthy controls, and whether SI time and hand motor speed interacted with the written version of the ...
متن کاملmultiple sclerosis functional composite as a measure of the effects of heat in multiple sclerosis
conclusions the results suggest that the msfc could be used as a simple tool to detect the negative effects of heat in patients with ms. results in the ms group the average msfc scores were -0.48 (sd 0.79) at baseline, -0.99 (sd 1.97) during heat exposure and -0.68 (sd 1.58) after a one-hour delay. the average msfc scores of the hc group were 0.58 (sd 0.42) at baseline, 0.66 (sd 0.43) during he...
متن کاملOutcome Measures in Multiple Sclerosis
The acquisition of a reliable and valid outcome measure in multiple sclerosis (MS) is one of the holy grails for clinician researchers working in the field. The current standard for measuring MS-related disability is the Expanded Disability Status Scale (EDSS), a nonlinear scale ranging from 0 (normal neurologic examination) to 10 (death due to MS) [1]. Widely incorporated into MS clinical tria...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal - Experimental, Translational and Clinical
سال: 2019
ISSN: 2055-2173,2055-2173
DOI: 10.1177/2055217319846141